The Analog Identification Methodology (AIM) is a downloadable software program that facilitates analog analysis and data identification in support of chemical assessment or read-across approaches to help scientists and chemical managers predict potential hazards of untested chemicals.

Key characteristics of the program include:

• Ability to conduct comprehensive structural analysis of chemicals using over 700 individual atoms, groups and super fragments indexed in a predefined database
• Uses structural analysis to match potential analogs from an inventory of over 86,000 chemicals with publicly available measured data and links to the data sources
• Ability to recode defined substitutions or exclusion rules for the refinement of analog search strategies

AIM software is available for free and is posted below as a downloadable software program without licensing requirements. Information on use and set-up is provided in the AIM User's Manual.

Analog Identification Methodology (AIM) Download(1 pg, 104 MB)

Disclaimer: Experimental data sources identified by AIM are not endorsed by EPA; nor does EPA vouch for the quality or accuracy of the data. Furthermore, professional judgement is needed to determine adequacy of analogs identified by AIM.

EPA Technical Contact:

Kelly E. Mayo-Bean, U.S. EPA
Risk Assessment Division (7403M)
1200 Pennsylvania Ave., N.W.
Washington, DC 20460-0001
Phone: 202-564-7662
Fax: 202-564-9063
e-mail: mayo.kelly@epa.gov

Kendra E. Moran, U.S. EPA
Risk Assessment Division (7403M)
1200 Pennsylvania Ave., N.W.
Washington, DC 20460-0001
Phone: 202-564-4322
Fax: 202-564-9063
e-mail: moran.kendra@epa.gov