Under section 612 of the Clean Air Act, EPA reviews substitutes in a comparative risk framework. To list new substitutes as acceptable, the Agency performs screening analysis of risks to human health and the environment from the use of various substitutes in different industrial and consumer uses that historically used ozone depleting substances.

• Protection of Stratospheric Ozone: New Listings for the Significant New Alternatives Policy Program in Refrigeration & Air Conditioning and Fire Protection Sectors (PDF)(1 pg, 457 K)