Acceptable Substitutes in Stand-Alone Units
You will need Adobe Reader to view some of the files on this page. See EPA’s About PDF page to learn more.Substitutes are reviewed on the basis of environmental and health risks, including factors such as ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptableacceptableThis designation means that a substitute may be used, without restriction, to replace the relevant ODS within the end-use specified. For example, HCFC-22 is an acceptable substitute for R-502 in industrial process refrigeration. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. and unacceptable
UnacceptableThis designation means that it is illegal to use a product as a substitute for an ODS in a specific end-use. For example, HCFC-141b is an unacceptable substitute for CFC-11 in building chillers. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. substitutes are updated several times each year. The list of acceptable substitutes are shown below.
Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.
Substitute | Trade Name | Retrofit/ New |
ODP![]() |
GWP![]() |
ASHRAE![]() (Safety Classification) |
SNAP Listing Date | Use Conditions |
---|---|---|---|---|---|---|---|
Ammonia Vapor Compression with Secondary Loop | N | 0 | 0 | B2 | March 18, 1994; September 5, 1996 |
||
FOR12A | FOR12A | R/N | 0 | 1,100 | A1 | December 18, 2000; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. |
FOR12B | FOR12B | R/N | 0 | 1,000 | A1 | December 18, 2000; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. |
Free Zone (HCFC Blend Delta) | Free Zone / RB-276 | R/N | 0.013 | 1,592 | A1 | September 5, 1996 | |
Freeze 12 | Freeze 12 | R/N | 0.013 | 1,606 | A1 | September 5, 1996 | |
FRIGC FR-12 (HCFC Blend Beta) | FRIGC FR-12 | R/N | 0.009 | 1,081 | A1 | February 8, 1996; February 24, 1998 |
|
G2018C | G2018C | R/N | 0.053 | 1,731 | A1 | September 5, 1996 | |
GHG-HP (HCFC Blend Lambda) | GHG-HP | R/N | 0.056 | 1,893 | A1 | February 8, 1996 | |
GHG-X4 | GHG-X4, Autofrost, Chill-it | R/N | 0.045 | 1,478 | A1 | September 5, 1996 | |
GHG-X5 | GHG-X5 | R/N | 0.032 | 2,377 | A1 | June 3, 1997 | |
HCFC-22 | 22 | R/N | 0.055 | 1,810 | A1 | March 18, 1994 | |
HCFC-22/HCFC-142b | R/N | 0.055-0.065 | 1,810-2,310 | A1 | June 3, 1997 | ||
HFC-134a | 134a | R/N | 0 | 1,430 | A1 | March 18, 1994; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. |
HFC-134a/HBr (92/8) | N | 0.0016 | N/A | A1 | May 23, 2001 | Only acceptable for use as the primary heat transfer fluid in secondary-loop equipment for not-in-kind replacements. | |
HFC-227ea | N | 0 | 3,220 | A1 | March 18, 1994; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. | |
HFE-7100 | N | 0 | 297 | A1 | December 18, 2000; June 16, 2010 |
Only acceptable for use as a secondary heat transfer fluid in not-in-kind systems. | |
HFE-7200 | N | 0 | 59 | N/A | December 18, 2000; June 16, 2010 |
Only acceptable for use as a secondary heat transfer fluid in not-in-kind systems. | |
Hot Shot | Hot Shot, Kar Kool | R/N | 0.098 | 3,337 | A1 | September 5, 1996 | |
Hot Shot 2 | Hot Shot 2 | R | 0 | 1,820 | A1 | October 4, 2011 | |
Ikon A | Ikon-12, Blend Zeta | R/N | 0 | N/A | A1 | June 19, 2000 | |
Ikon B | R/N | 0 | N/A | A1 | December 6, 1999 | ||
R-125/R-290/R-134a/R-600a (55.0/1.0/42.5/1.5) | ICOR AT-22 | R/N | 0 | 2,530 | A1 | June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-290 (Propane) | N | 0 | 3 | A3 | December 20, 2011 | Detailed conditions apply – see Rule | |
R-401A | SUVA MP-39 | N | 0.037 | 1,182 | A1 | January 13, 1995 | |
R-401B | SUVA MP-66 | N | 0.040 | 1,288 | A1 | January 13, 1995 | |
R-402A | HP-80 | R/N | 0.019 | 2,746 | A1 | March 18, 1994 | |
R-402B | HP-81 | R/N | 0.03 | 2,379 | A1 | March 18, 1994 | |
R-404A | HP-62 | R/N | 0 | 3,920 | A1 | March 18, 1994; December 20, 2002; July 20, 2015 |
Unacceptable in retrofit equipment as of July 20, 2016. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-406A | GHG | R | 0.057 | 1,900 | A2 | August 26, 1994 | |
R-407A | Klea 60, Klea 407A | R/N | 0 | 2,110 | A1 | August 26, 1994; January 2, 2009; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-407B | Klea 61 | R/N | 0 | 2,800 | A1 | August 26, 1994; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-407C | Suva 407C, Klea 407C | R/N | 0 | 1,770 | A1 | February 8, 1996; December 20, 2002; August 21, 2003 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-407F | Genetron Performax LT | R/N | 0 | 1,820 | A1 | October 4, 2011; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-408A (HCFC Blend Epsilon) | R | 0.026 | 55 | A1 | August 26, 1994 | ||
R-409A (HCFC Blend Gamma) | R-409A (HCFC Blend Gamma) | R | 0.047 | 1,558 | A1 | August 26, 1994 | |
R-410A | AZ-20, Suva 9100, Puron | N | 0 | 2,090 | A1 | February 8, 1996; December 20, 2002; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-410B | N | 0 | 2,230 | A1 | February 8, 1996; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. | |
R-411A | R/N | 0.048 | 1,600 | A2 | February 8, 1996 | ||
R-411B | R/N | 0.052 | 1,700 | A2 | February 8, 1996 | ||
R-417A | ISCEON 59, NU-22 | R/N | 0 | 2,350 | A1 | December 6, 1999; December 20, 2002; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-420A | Choice R-420A | R/N | 0.008 | 1,536 | A1 | October 1, 2004 | |
R-421A | Choice R-421A | R/N | 0 | 2,630 | A1 | September 28, 2006; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-421B | Choice R-421B | R/N | 0 | 3,190 | A1 | September 28, 2006; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-422A | ISCEON 79 | R/N | 0 | 3,140 | A1 | October 1, 2004; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-422B | ICOR XAC1, NU-22B | R/N | 0 | 2,530 | A1 | March 29, 2006; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-422C | ICOR XLT1 | R/N | 0 | 3,390 | A1 | March 29, 2006; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-422D | ISCEON MO29 | R/N | 0 | 2,730 | A1 | September 28, 2006; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-424A | RS-44 | R/N | 0 | 2,440 | A1 | September 28, 2006; June 16, 2010 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-426A | RS-24 | R/N | 0 | 1,510 | A1 | September 28, 2006; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. |
R-427A | Forane 427A | R | 0 | 2,140 | A1 | January 2, 2009; June 16, 2010 |
|
R-428A | RS-52 | R/N | 0 | 3,610 | A1 | October 4, 2007; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-434A | RS-45 | R/N | 0 | 3,250 | A1 | October 4, 2007; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-437A | KDD6, ISCEON MO49 Plus | R/N | 0 | 1,810 | A1 | January 2, 2009; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-438A | KDD5, ISCEON MO99 | R/N | 0 | 2,270 | A1 | October 4, 2007; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-441A | N | 0 | <5 | A3 | April 10, 2015 | Detailed conditions apply - see Rule | |
R-448A | Solstice® N-40 | R/N | 0 | 1,387 | A1 | July 16, 2015 | Low temperature (i.e., temperatures at or below 32°F (0 °C)) stand-alone equipment only. |
R-449A | Opteon® XP 40 | R/N | 0 | 1,400 | A1 | July 16, 2015 | Low temperature (i.e., temperatures at or below 32°F (0 °C)) stand-alone equipment only. |
R-449B | Forane® 449B | R/N | 0 | 1,412 | A1 | October 11, 2016 | Low temperature (i.e., temperatures at or below 32°F (0 °C)) stand-alone equipment only. |
R-450A | Solstice® N-13 | R/N | 0 | 601 | A1 | October 21, 2014 | |
R-507, R-507A | AZ-50 | R/N | 0 | 3,990 | A1 | March 18, 1994; December 20, 2002; September 30, 2009; July 20, 2015 |
Unacceptable in retrofit equipment as of July 20, 2016. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. |
R-513A | Opteon® XP 10 | R/N | 0 | 630 | A1 | July 16, 2015 | Low temperature (i.e., temperatures at or below 32°F (0 °C)) and medium temperature (i.e., temperatures above 32°F (0 °C)) stand-alone equipment. |
R-600a (Isobutane) | N | 0 | 3 | A3 | April 10, 2015 | Detailed conditions apply - see Rule | |
R-744 (Carbon Dioxide, CO2) | N | 0 | 1 | A1 | September 30, 2009 | ||
RS-24 (2002 formulation) | R/N | 0 | 1,510 | A1 | December 20, 2002; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. | |
RS-44 (2003 formulation) | R/N | 0 | 2,420 | A1 | June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. Unacceptable in new Stand-Alone Low-Temperature Units as of January 1, 2020. | |
Self-chilling cans using CO2 | N | 0 | 1 | A1 | February 24, 1998 | ||
SP34E | SP34E | R/N | 0 | <1,470 | A1 | December 18, 2000; June 16, 2010; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. |
THR-02 | R/N | 0 | N/A | A1 | December 6, 1999 | ||
THR-03 | R/N | 0 | N/A | A1 | December 6, 1999; July 20, 2015 |
Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity below 2,200 Btu/hour and not containing a flooded evaporator as of January 1, 2019. Unacceptable in new Stand-Alone Medium-Temperature Units with a compressor capacity equal to or greater than 2,200 Btu/hour and Stand-Alone Medium-Temperature Units containing a flooded evaporator as of January 1, 2020. | |
THR-04 | R/N | >0 | N/A | A1 | June 8, 1999 |
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