You will need Adobe Reader to view some of the files on this page. See EPA’s About PDF page to learn more.Substitutes are reviewed on the basis of environmental and health risks, including factors such as ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptableacceptableThis designation means that a substitute may be used, without restriction, to replace the relevant ODS within the end-use specified. For example, HCFC-22 is an acceptable substitute for R-502 in industrial process refrigeration. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. and unacceptableUnacceptableThis designation means that it is illegal to use a product as a substitute for an ODS in a specific end-use. For example, HCFC-141b is an unacceptable substitute for CFC-11 in building chillers. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. substitutes are updated several times each year. The list of acceptable substitutes are shown below.

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

Substitute	Trade Name	Retrofit/New	ODPODPA number that refers to the amount of ozone depletion caused by a substance. The ODP is the ratio of the impact on ozone of a chemical compared to the impact of a similar mass of CFC-11. Thus, the ODP of CFC-11 is defined to be 1.0. Other CFCs and HCFCs have ODPs that range from 0.01 to 1.0. The halons have ODPs ranging up to 10. Carbon tetrachloride has an ODP of 1.2, and methyl chloroform's ODP is 0.11. HFCs have zero ODP because they do not contain chlorine. A table of all ozone-depleting substances (https://www3.epa.gov/ozone/science/ods/index.html) shows their ODPs, GWPs, and CAS numbers.	GWPGWPThe index used to translate the level of emissions of various gases into a common measure in order to compare the relative radiative forcing of different gases without directly calculating the changes in atmospheric concentrations. GWPs are calculated as the ratio of the radiative forcing that would result from the emissions of one kilogram of a greenhouse gas to that from the emission of one kilogram of carbon dioxide over a period of time (usually 100 years). Gases involved in complex atmospheric chemical processes have not been assigned GWPs. See lifetime.	ASHRAEASHRAEASHRAE is an international organization that establishes standards for the uniform testing and rating of heating, ventilation, air conditioning, and refrigeration equipment. It also conducts related research, disseminates publications, and provides continuing education to its members. Designation (Safety Classification)	SNAP Listing Date	Use Conditions
Evaporative Cooling		N	0	N/A	N/A	March 18, 1994
Free Zone (HCFC Blend Delta)	Free Zone / RB-276	R/N	0.013	1,592	A1	May 22, 1996; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Rule.
Freeze 12	Freeze 12	R/N	0.013	1,606	A1	October 16, 1996; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Rule.
R-416A	FRIGC FR-12, HCFC Blend Beta	R/N	0.009	1,081	A1	June 13, 1995; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Rule.
GHG-HP (HCFC Blend Lambda)	GHG-HP	R/N	0.056	1,893	A1	October 16, 1996; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Rule.
R-414A	GHG-X4, HCFC Blend Xi, Autofrost, Chill-it	R	0.045	1,478	A1	October 16, 1996; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Rule.
GHG-X5	GHG-X5	R/N	0.032	2,377	A1	June 3, 1997; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Notice.
HFC-134a	134a	R/N	0	1,430	A1	March 18, 1994; July 20, 2015	Unacceptable in New Light-Duty Systems as of Model Year (MY) 2021, except where allowed under a narrowed use limit through MY 2025. Acceptable, subject to narrowed use limits, for vehicles exported to countries with insufficient servicing infrastructure to support other alternatives, for MY 2021 through MY 2025. Unacceptable for all newly manufactured vehicles as of MY 2026. Detailed conditions apply - see Rule.
HFC-152a		N	0	124	A2	June 12, 2008	Detailed conditions apply - see Rule
HFO-1234yf		N	0	4	A2L	March 29, 2011; December 1, 2016	Acceptable for use in newly manufactured passenger cars, light-duty trucks, medium-duty passenger vehicles, heavy-duty pickup trucks, and complete heavy-duty vans. Detailed conditions apply - see Rules
R-414B	Hot Shot, Kar Kool	R/N	0.098	3,337	A1	October 16, 1996; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Rule.
Ikon A	Ikon-12, Blend Zeta	R/N	0	N/A	A1	May 22, 1996	Detailed conditions apply - see Rule
R-401C		R/N	0	933	A1	June 13, 1995
R-406A	GHG	R/N	0.057	1,900	A2	October 16, 1996; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Rule.
R-426A	RS-24	R/N	0	1,510	A1	September 28, 2006; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Notice.
R-744 (Carbon Dioxide, CO2)		N	0	1	A1	June 6, 2012	Detailed conditions apply - see Rule
RS-24 (2002 formulation)		R/N	0	1,510	A1	December 20, 2002	Detailed conditions apply - see Notice
Small auxiliary power units that include an engine, electrical alternator, water pump, air conditioning compressor and a heat exchanger used in tractor trailers in conjunction with passenger compartment climate control systems that already use an acceptable substitute refrigerant.		R/N	0	N/A	N/A	June 19, 2000
SP34E	SP34E	R/N	0	<1,470	A1	December 18, 2000; May 23, 2001; July 20, 2015	Unacceptable in New Light-Duty Systems as of MY 2017. Detailed conditions apply - see Notice; Use of new fittings for small refrigerant cans required.
Stirling Cycle		N	0	N/A	N/A	March 18, 1994

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