CatReg Version 3.0.1.5 ReadMe

CONTENTS
CATREG REQUIRES R
CATREG 3.0.1.5 SYSTEM REQUIREMENTS
INSTALLING CATREG 3.0.1.5 
KNOWN CATREG ISSUES
CATREG SUPPORT
RECEIVE UPDATES ON NEW RELEASES
LATE-BREAKING INFO NOT IN THE USER GUIDE


CATREG REQUIRES R All versions of CatReg, including Version 3.0.1.5, rely
on the open source package R to perform all statistical calculations. To
use CatReg 3.0.1.5 you must have version 3.2.2 or later of R and Microsoft
Windows 7 or later operating system installed on your computer. You can
download R from http://www.r-project.org/.

Versions of CatReg prior to Version 3.0.1.5 can run on any computer
operating system on which R can be installed.


CATREG 3.0.1.5 SYSTEM REQUIREMENTS
* 16 Megabytes of RAM
* Microsoft Windows 7 or later.
* Microsoft .NET 4.6 or later. If your computer is set up to allow or be
  notified of downloads of Microsoft software, then it is likely that that
  version of the .NET framework is already installed. Otherwise, you can
  download and install the latest version from the Microsoft .NET Home
  (http://www.microsoft.com/net/default.aspx).
* R statistical software version 3.2.2 or later for Windows. Download and
  install the latest version from https://cran.r-project.org/bin/windows/base/.
  CatReg relies on the open source package R for Windows to perform all
  statistical calculations.

NOTE: There are no plans for Mac or Linux versions of CatReg 3.0.1.5 at this time.


INSTALLING CATREG 3.0.1.5 You do not need to uninstall previous versions
of CatReg. You can run this version of CatReg along with earlier versions.

1. Locate the CatReg.zip file you downloaded. 
2. In Windows Explorer, double-click the downloaded .zip file. Drag and
   drop the CatReg folder from the .zip file to the directory of your
   choice on your computer.
3. Select the CatReg.exe file to start the program.

When installing the CatReg application folder, you should:
* Place the CatReg application folder (and its subfolders) in the simplest,
  shortest directory possible.
* Have administrative rights for the folder.
* Ensure there are no special characters or spaces in the folder names.

For most EPA users, the preferred path would be C:\Users\[EPA user's LAN ID];
for non-EPA users, this could be as simple as C:\.


KNOWN CATREG ISSUES
* CatReg does not have international capabilities at this time. You must
  set your Windows Region and Language control panel to "English
  (United States)."
* When stratification results in more than five categories, CatReg plots
  do not display the data points for categories beyond the 5th item.
* The deviance plot (devplot) works only for the "Observation #" option
  when the model specifications specify Linear Dose.
* CatReg only estimates "Extra Risk" at this time.


CATREG SUPPORT If you have problems or concerns, please contact us using
our Help Desk Form (http://bmds.epa.gov/eticket/). Or, from within CatReg,
select Help > Support to open a support ticket.


RECEIVE UPDATES ON NEW RELEASES
Registration is not required to download the software. However, to learn
about new releases or important information, you can sign up at
https://www.epa.gov/bmds/forms/get-latest-benchmark-dose-software-bmds-news.


LATE-BREAKING INFORMATION NOT IN THE USER GUIDE
* CatReg uses a relative convergence tolerance of 1.5E-8 when calling the
optimizer routine to find the parameter estimates. Note: the relative
convergence tolerance will be larger on computers with a floating point
precision coarser than 2.2E-16.