Research Grants

January NIEHS/EPA Children's Centers 2014 Webinar Series

Title: NIEHS/EPA Children's Centers 2014 Webinar Series
Date: January 8, 2014
1:00 p.m. - 2:30 p.m. EST
Location: Webinar
Purpose:

Join us for this month's webinar presenting research from the University of California, Berkeley. The webinar features presentations and interactive discussions including recent findings and new developments in children’s environmental health.

The mission of the Children’s Centers program is to reduce children’s health risks, protect them from environmental threats and to promote children’s health and well-being in the communities where they learn, live and play.

Featured Speakers:

Stephen M. RappaportStephen M. Rappaport
Center for Integrative Research on Childhood Leukemia and the Environment (CIRCLE)
Presentation Title: Using Newborn Dried Blood Spots to Estimate In Utero Exposures to Chemicals
Presentation Summary:

  1. What is the exposome and how can we use newborn dried blood spots (DBS) to investigate exposures received by babies during pregnancy?
  2. What are protein adducts and how can they be used to get information about exposures to a group of toxins called "reactive electrophiles"?
  3. Is it possible to measure protein adducts in a small portion of a DBS representing 1/10th of a drop of blood (because this is all we have to work with)?

Catherine MetayerCatherine Metayer
Center for Integrative Research on Childhood Leukemia and the Environment (CIRCLE)
Presentation Title: Paternal and Maternal Tobacco Smoking and the Risk of Leukemia in the Offspring
Presentation Summary:

  1. Leukemia is a heterogeneous disease and the risk factors are likely to be subtype-specific.
  2. Carcinogens in tobacco smoke can damage the parents' germ-cells (before conception) and child's somatic cells (during pregnancy and after birth).
  3. Epidemiologic data support the "two" hit model of leukemogenesis for childhood leukemia.
Contact: Nica Louie (louie.nica@epa.gov); 703-347-8125