A meeting of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances (NAC/AEGL Committee) was held on April 26-28, 2000, in Piscataway, NJ.

The NAC/AEGL Committee has now instituted the development of AEGLs for 10-minute exposure periods for all chemicals scheduled for AEGL development. This 10-minute exposure period will be in addition to the current exposure periods of 30-minutes, 1 hour, 4 hours, and 8 hours. The new 10-minute numbers will be developed for all chemicals previously addressed by the NAC/AEGL Committee, as well as all future chemicals to come before the NAC/AEGL Committee.

At this meeting, the NAC/AEGL Committee addressed various aspects of the acute toxicity and the development of AEGLs for all exposure periods for the following chemicals: Agent HD (sulfur mustard); bromine; cis- and trans-1,2- dichloroethylene; HCFC-141b; HFC-134a; hydrogen cyanide; hydrogen fluoride; hydrogen sulfide; Otto fuel II, uranium hexafluoride; phosphine; 1,1,1-trichloroethane. There was also a discussion of and the development of 10-minute AEGL values for the following chemicals for which the other exposure periods have already been developed at the proposed level: Allyl amine; carbon tetrachloride; chlorine trifluoride; crotonaldehyde; cyclohexylamine; dimethyldichlorosilane; epichlorohydrin; ethylenediamine; ethylene oxide; ethyleneimine; hydrogen chloride; iron pentacarbonyl; methyl isocyanate; methyl mercaptan; methyltrichlorosilane; nickel carbonyl; nitric acid; peracetic acid; phosgene; phosphorus oxychloride; phosphorus trichloride; piperidine; propyleneimine; toluene; and toluene diisocyanate.

• AEGL Meeting Minutes 04/26-28, 2000 (PDF)(194 pp, 7 MB)